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Amino acid Interface Fitness (AIF) Matrix

The 20X20 amino acid interface fitness (AIF) matrix which is also referred to as interface fitness score (IFS) between pairs of amino acids in the epitope and paratope. Paratope amino acids are indicated on the left side and epitope amino acids are indicated on the top side. The propensity data were generated using 84 non‐redundant antigen‐antibody complexes: Reference