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Swine Flu Transmission Mutation Risk

Fortunately the spread of H1N1 was far less rapid and wide-spread than many had feared. However, with a key mutation, the virus could easily adapt far rapid transmission. Inefficient binding to human respiratory tract receptors affected the virus efficacy and spread. However, with just a single mutation, the virus could prove far more deadly. Given the rapid evolution of influenza, H1N1 should be closely monitored.

  • H1N1 virus particles [image courtesy NIAID]
  • Structural model of CA/04 HA bound to α2-6 oligosaccharide [source]
  • Analysis of Cal0409 NA [source]